Clinical trial simulations– an essential tool in drug development

The clinical development of investigational drugs is a complex and expensive process. The costs can be affected by decisions that are taken as clinical trials progress from one stage to the next (eg dose selection studies and transitions from Phase 2 to Phase 3 clinical trials). Clinical trial simulations are being increasingly viewed as an integral part of clinical development programmes and can be used to improve the understanding and decision making at every stage of drug development. In this article we provide an example led overview illustrating the impact that simulations can have along the drug development timeline.